Secondary and tertiary transplantation shows maintenance of engraftment and poly(I:C) treatment leads to selection of GFP+ donor cells. (A) Peripheral blood GFP⁺ chimerism at indicated time points following secondary transplant with (B) lineage analysis of the peripheral blood postsecondary transplant. (C) Peripheral blood GFP⁺ chimerism at indicated time points following tertiary transplant with (D) lineage analysis of the peripheral blood posttertiary transplant. (E) Enhanced IUHCT peripheral blood donor chimerism 1 month after poly(I:C) treatment. (F) Peripheral blood donor chimerism following IUHCT at the indicated time points following poly(I:C) treatment. (G) BM analysis of poly(I:C) treated mice at 6 months posttreatment. (H) Complete blood counts 6 months post poly(I:C) treatment. WBM, whole bone marrow.