Figure 1.
IUHCT results in sustained engraftment in Fancc–/– mice. (A) Flow cytometry of peripheral blood from E14-injected Fancc–/– and WT fetuses. (B) Engraftment observed across cell types. (C) Lineage composition of GFP+ engrafted cells. (D) BM GFP+ cell engraftment. (E) Complete blood counts of injected and noninjected Fancc–/– and WT animals. (F) Representative BM CFU-Cs. (G) Representative femur GFP+ staining from 6 months post-IUHCT. ∗∗∗P < .001; ∗∗P < .002; ∗P < .033; ns, nonsignificant.

IUHCT results in sustained engraftment in Fancc–/– mice. (A) Flow cytometry of peripheral blood from E14-injected Fancc–/– and WT fetuses. (B) Engraftment observed across cell types. (C) Lineage composition of GFP+ engrafted cells. (D) BM GFP+ cell engraftment. (E) Complete blood counts of injected and noninjected Fancc–/– and WT animals. (F) Representative BM CFU-Cs. (G) Representative femur GFP+ staining from 6 months post-IUHCT. ∗∗∗P < .001; ∗∗P < .002; ∗P < .033; ns, nonsignificant.

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