OS and progression/relapse-free survival stratified by rDRI. Probability of OS stratified by rDRI was grouped into 3 (low, intermediate, and high-very high) in the European cohort (A) and in the Japanese cohort (B). Probability of PFS stratified by rDRI was grouped into 3 (low, intermediate, high-very high) in the European cohort (C) and in the Japanese cohort (D).