AIHA in RAG deficiency. (A) Distribution of clinical phenotypes. (B) Relative activities of RAG1 mutants across different clinical phenotypes (n = allele number). (C) Frequencies of autoimmune cytopenias and other autoimmune manifestations. (D-F) Comparisons of total lymphocyte, CD8⁺ T cell and CD56⁺ NK cell counts between patients with and without Evans syndrome (statistical significance, ∗P < .05, ∗∗P < .01). (G) Kaplan-Meier curve of the overall survival.