Ig-HTS clonotypic V(D)J sequence identity overlap analysis overview. (A) Histologic representation within the clinical cohort. (B) Schematic depication of analyses performed. (C) Donut charts depicting the proportion of patients with unique or non-unique heavy chain (blue) and light chain (purple) clonotypes detected by clonoSEQ. (D) Each column depicts a non-unique dominant lymphoma light chain clonotype, as determined by clonoSEQ. Each row represents an individual immunoSEQ BCR repertoire from the control immuneACCESS database. The frequency at which the clonoSEQ clonotype occurs within each control repertoire is depicted in blue. Clonotypes not found in a given control repertoire occupy white squares. The bottom bar chart sums up the percent of immuneACCESS subjects (out of 71 total) that overlap with each clonotype.