ACR status in a cohort of children and adolescents with SCA from Minas Gerais, Brazil. (A) Prevalence of intermittent and PA in the longitudinal analysis. (B) Age of participants by albuminuria category; each horizontal bar shows mean and standard deviation; statistically significant P values indicated by an asterisk (∗). (C) Frequency of participants with PA by categories of age at the confirmatory ACR measurement. (D) Variability from baseline to the follow-up ACR measurement in participants who had an ACR ≥ 100 mg/g at the enrollment. Three data points are outside the axis limits.