Platelet aggregation and intraplatelet levels of fibrinogen and fibronectin are unaltered in Fga^EK mice. Aggregation traces of platelet-rich plasma collected from Fga^WT/WT, Fga^WT/EK, Fga^EK/EK, and Fga^−/− mice after stimulation with (A) 5 μM adenosine 5′-diphosphate (ADP; n = 4 per genotype) or (B) 250 μM protease-activated receptor 4 activating peptide (Par4p; n = 4 per genotype). (C) Western blot (WB) analyses for fibrinogen, fibronectin, and actin of platelet lysates harvested from Fga^WT/WT, Fga^WT/EK, and Fga^EK/EK mice. Quantification of platelet (D) fibrinogen and (E) fibronectin from the WBs. (F) Western blot analyses for fibrinogen, fibronectin, and albumin of plasma harvested from Fga^WT/WT, Fga^WT/EK, and Fga^EK/EK mice (n = 3 per genotype). Quantification of plasma (G) fibrinogen and (H) fibronectin from the WBs. Data are presented as the mean ± standard error of the mean (SEM), and analyzed using one-way analysis of variance (ANOVA).