Figure 1.
Prevalence of acquired N-linked glycosylation motifs during FL evolution. Stacked bars showing proportions of N-motif–positive tumor cells with the N-motif of the dominant tumor clone (dominant N-motif, red), N-motif–positive tumor cells with a different acquired N-motif (with a different amino acid sequence and/or location) compared with that of the dominant tumor clone (nondominant N-motif, green), and N-motif–negative tumor cells (blue) across multiple tumor sites and time points for 17 patients with FL. Bars reflect data from all available time points for a given site (see supplemental Tables 1 and 2 for detailed information). N-motif–positive cells can harbor N-motifs in Ig heavy and/or light chain V(D)J.