Reanalysis of patients with high-risk FL from analysis A and analysis B. (A) Identified proteins comparing nt-FL and st-FL samples from the high-risk group identified in analysis A. The x-axis represents the fold changes as transformed by log₂(st-FL/nt-FL); thus, red dots mark upregulated proteins at P < .05 and a fold change >20%, whereas green dots mark downregulated proteins at P < .05 and a fold change <20%. To allow for better visualization of highly significant data points, the negative logarithm (log₁₀) of the P values are plotted on the y-axis. Horizontal lines mark P values of P < .05 and P < .01, respectively. (B) 3D PCA based on differentially expressed proteins at P < .01 identified in high-risk group in analysis A. (C) Hierarchal clustering based on differentially expressed proteins at P < .01 identified in the high-risk group from analysis A. (D) Identified proteins comparing nt-FL and st-FL samples from the high-risk group identified from analysis B. Fold change as transformed by log2(st-FL/nt-FL). Red, upregulated at P < .05 threshold; green, downregulated at P < .05 threshold. Horizontal lines mark P values of P < .05 and P < .01, respectively. (E) 3D PCA based on differentially expressed proteins at P < .05 in the high-risk group from analysis B. (F) Hierarchal clustering based on differentially expressed proteins at P < .05 in the high-risk group from analysis B.