Effects of 2 variants on platelet count (y-axis) and mean platelet volume (x-axis). RUNX1 rs200431130 p.Met52Lys (n = 164 individuals with minor allele) and MECOM rs200049869 p.Met1005Val (n = 127). Values are mean ± 95% confidence interval (CI), and units are SD. The figure has been adapted from Figure 3B in the article by Stefanucci et al that begins on page 2055.