Clinical case 3: disseminated intravascular coagulation (DIC). (A) Patient with pneumonia develops a rapid drop in platelet count (blue) and increased white count (orange) with microangiopathic hemolytic anemia and high D dimer. Thrombotic thrombocytopenic purpura (TTP) was considered given neurologic symptoms, and plasmapheresis was initiated. The patient recovered with antibiotic treatment for pneumonia and sepsis. (B) International Society on Thrombosis and Haemostasis (ISTH) disseminated intravascular coagulation (DIC) score high, compatible with overt DIC.