Figure 3.
Hypothesis on how pyruvate kinase activation, through enhanced glycolysis and increased in ATP availability, reduces oxidative damage and hemolysis and improves ineffective erythropoiesis and dysregulated iron metabolism, thereby improving anemia and iron overload.

Hypothesis on how pyruvate kinase activation, through enhanced glycolysis and increased in ATP availability, reduces oxidative damage and hemolysis and improves ineffective erythropoiesis and dysregulated iron metabolism, thereby improving anemia and iron overload.

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