The “YEARS” items, which were included in the Artemis study diagnostic algorithm (Netherlands Trial Register number, NL5726).¹²  In this study, pulmonary embolism was excluded in people with no YEARS items and a D-dimer level <1000  ng/mL, or ≥1 YEARS item and D-dimer <500  ng/mL. CUS was performed if there were clinical signs of DVT.