Considerations in the treatment of patients with SM-AHN. BM, bone marrow; FBC, full blood count; HR, high risk; MPN, myeloproliferative neoplasms. Reproduced with permission from Radia DH, Moonim MT. Update on diagnostic approaches and therapeutic strategies in systemic mastocytosis. Best Pract Res Clin Haematol. 2022;35(2):101380. doi:10.1016/j.beha.2022.101380.