Figure 2.
MC mediator release with biological and clinical consequences. CRH, corticotropin-releasing hormone; CysLTs, cysteinyl leukotrienes; IL-6/8/33, interleukin 6/8/33; PAF, platelet-activating factor; PGD2, prostaglandin D2; RANKL, receptor activator of nuclear factor kβ ligand; TNF, tumor necrosis factor; VIP, vasoactive intestinal peptide. Adapted from Theoharides et al.3

MC mediator release with biological and clinical consequences. CRH, corticotropin-releasing hormone; CysLTs, cysteinyl leukotrienes; IL-6/8/33, interleukin 6/8/33; PAF, platelet-activating factor; PGD2, prostaglandin D2; RANKL, receptor activator of nuclear factor kβ ligand; TNF, tumor necrosis factor; VIP, vasoactive intestinal peptide. Adapted from Theoharides et al.3 

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