Patients with AML can be categorized in 2 groups based on TERRA expression. (A) Unsupervised hierarchical clusterization of AML samples. Both rows and columns are clustered using Euclidean distance. Two groups were formed, high-TERRA expression AMLs and low-TERRA expression AMLs. (B) Box plot of telomere length T/S ratio. (C) Box plot of TRF2 expression. (D) Box plot of ATRX expression. (E) Box plot of RNaseH1. (F) Box plot of RNaseH2. (G) Box plot of TERT expression. ∗P < .05. ns, nonsignificant.