Clinicopathologic characteristics of HGBL-NOS. (A) Prevalence of the most common immunophenotypes with or without MYC rearrangement (only phenotypes with n ≥ 2 are shown); (B) prevalence of MYC and/or BCL2 alterations, via FISH, in morphologic subtypes; distribution of characteristics based on panel B tumor morphology and (C) cell of origin determined via immunohistochemistry (P values from Fisher exact test).