Gene dysregulation and influence of CN changes in CK-AML. (A) Schematic overview of our differentially expressed genes (DEG) analysis that integrates gene expression (GE) with CN information. CN ↓, CN loss; CN ↑, CN gain; GE ↓, gene downregulation; GE ↑, gene upregulation. (B) Number of genes from the 30 “downregulated candidate genes” that were downregulated in the respective case. (C) Number of genes from the 30 downregulated candidate genes that were downregulated and showed a CN loss at the gene locus.