Comparison of the IPSS-M and IPSS-R. (A) Stratification of our cohort based on IPSS-M for OS, LFS, and PFS. (B) Model discrimination measured by the concordance index via bootstrapping for the IPSS-R (light blue) and the IPSS-M system (red) across all the 3 outcomes end points (LFS, OS, and PFS) for the full cohort, treated vs untreated patients, males vs females, and ≥60 vs <60 years old. (C) The cumulative AUC differences (ΔAUC) based on IPSS-M between treated and untreated patients (y-axis) is plotted against the follow-up time intervals of 10 months (x-axis).