CAR-ADR T cells protect from xenogeneic GVHD and prevent leukemia progression in vivo. (A) Schematic of the model setup for panels B-D (NALM6). (B) Tumor luminescence at specified time points. Each line represents data from an individual animal. (C) Animal body weight (normalized to weight on day 0 of the same animal) at specified time points. Each line represents data from an individual animal. In panels B-C, causes of death are indicated for each respective experimental group. (D) Animal survival over time. P values were calculated using log-rank test. (E) Schematic of the model setup for panels F-H (BV173). (F) Tumor luminescence at specified time points. Each line represents data from an individual animal. (G) Animal body weight (normalized to weight on day 0 of the same animal) at specified time points. Each line represents data from an individual animal. In panels F-G, causes of death are indicated for each respective experimental group. (H) Animal survival over time. P values were calculated using log-rank test.