Figure 3.
OX40.ADR T cells suppress fatal xenogeneic GVHD in vivo. (A) Schematic of model setup for panels B-E. (B) Absolute counts of specified populations on day 11 post PBMC injection. Mean ± SD values are shown. Each dot represents data from an individual animal. P values were calculated using unpaired t test. (C) Animal body weight (normalized to weight on day 0 of the same animal) at specified time points. Each line represents data from an individual animal. (D) GVHD clinical scores at specified time points. Each line represents data from an individual animal. (E) Animal survival over time. P values were calculated using a log-rank test. TBI, total body irradiation.

OX40.ADR T cells suppress fatal xenogeneic GVHD in vivo. (A) Schematic of model setup for panels B-E. (B) Absolute counts of specified populations on day 11 post PBMC injection. Mean ± SD values are shown. Each dot represents data from an individual animal. P values were calculated using unpaired t test. (C) Animal body weight (normalized to weight on day 0 of the same animal) at specified time points. Each line represents data from an individual animal. (D) GVHD clinical scores at specified time points. Each line represents data from an individual animal. (E) Animal survival over time. P values were calculated using a log-rank test. TBI, total body irradiation.

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