Figure 2.
PDPN expression and circulating PDPN in NMH newly diagnosed adult-type diffuse glioma cases. (A) Representative photomicrographs of PDPN IHC, on a semiquantitative scale from 0 (negative) to 4 (strongest). Scale bar = 50 μm. (B) PDPN IHC scores across the 3 subsets of adult-type diffuse gliomas. (C) Cumulative VTE incidence according to glioma PDPN IHC score. (D) Circulating PDPN, at the time of initial surgery, across the 3 subsets of patients with adult-type diffuse glioma. (E) Cumulative VTE incidence according to circulating PDPN at the time of initial surgery. (F) Linear regression plot of circulating TF-MV activity vs circulating PDPN at the time of initial surgery. Astro, IDHmut grade 2 to 4 astrocytoma; GBM, IDHwt glioblastoma; oligo, IDHmut, 1p/19q-codeleted WHO grade 2 to 3 oligodendroglioma.

PDPN expression and circulating PDPN in NMH newly diagnosed adult-type diffuse glioma cases. (A) Representative photomicrographs of PDPN IHC, on a semiquantitative scale from 0 (negative) to 4 (strongest). Scale bar = 50 μm. (B) PDPN IHC scores across the 3 subsets of adult-type diffuse gliomas. (C) Cumulative VTE incidence according to glioma PDPN IHC score. (D) Circulating PDPN, at the time of initial surgery, across the 3 subsets of patients with adult-type diffuse glioma. (E) Cumulative VTE incidence according to circulating PDPN at the time of initial surgery. (F) Linear regression plot of circulating TF-MV activity vs circulating PDPN at the time of initial surgery. Astro, IDHmut grade 2 to 4 astrocytoma; GBM, IDHwt glioblastoma; oligo, IDHmut, 1p/19q-codeleted WHO grade 2 to 3 oligodendroglioma.

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