TF expression and circulating TF-MV activity in NMH newly diagnosed adult-type diffuse glioma cases. (A) Cumulative VTE incidence according to glioma genotype. (B) Representative photomicrographs of TF IHC, on a semiquantitative scale from 0 (negative) to 4 (strongest). Scale bar = 50 μm. (C) TF IHC scores across the 3 subsets of adult-type diffuse gliomas. (D) Cumulative VTE incidence according to glioma TF IHC score. (E) Circulating TF-MV activity, at the time of initial surgery, across the 3 subsets of patients with adult-type diffuse glioma. (F) Cumulative VTE incidence according to circulating TF-MV activity at the time of initial surgery. Astro, IDH^mut grade 2 to 4 astrocytoma; GBM, IDH^wt glioblastoma; oligo, IDH^mut, 1p/19q-codeleted WHO grade 2 to 3 oligodendroglioma.