GM networks of the higher- and lower-diversity groups before allo-HSCT. Correlation networks of interactions reconstructed from genus-level compositional data in the lower- (A) and higher- (B) diversity groups before allo-HSCT. Red lines represent negative interactions, whereas solid gray lines stand for positive ones. Node size is proportional to the overabundance value of the corresponding genus in the GM configuration of the diversity group considered. Only nodes corresponding to genera showing overabundance ≥1.4 were displayed. Labels were displayed only for genera showing an overabundance of at least 1.5. The 5 different modules detected according to a statistical mechanics spin-glass model and simulated annealing are noted with labels. (C) Values of computed network features (ie, modularity, N:P ratio, and TC).