Figure 1.
Study design. ∗In the lenalidomide arm, venous thromboembolism prophylaxis with either low-molecular weight heparins or aspirin is mandatory (according to institutional guidelines). †Rituximab (375 mg/m2) and CHOP chemotherapy included cyclophosphamide (750 mg/m2 IV), doxorubicin (50 mg/m2 IV), and vincristine (1.4 mg/m2 [maximum dose = 2 mg] IV) on day 1 of every 21-day cycle and prednisone/prednisolone (100 mg/day PO) on days 1 to 5. The day 1 steroid dose being part of CHOP (100 mg prednisone/prednisolone, or equivalent, PO or IV) could be used as a further component of premedication before tafasitamab infusion. L, lenalidomide; NOS, not otherwise specified; PO, orally; R, randomized; T, tafasitamab.

Study design. ∗In the lenalidomide arm, venous thromboembolism prophylaxis with either low-molecular weight heparins or aspirin is mandatory (according to institutional guidelines). Rituximab (375 mg/m2) and CHOP chemotherapy included cyclophosphamide (750 mg/m2 IV), doxorubicin (50 mg/m2 IV), and vincristine (1.4 mg/m2 [maximum dose = 2 mg] IV) on day 1 of every 21-day cycle and prednisone/prednisolone (100 mg/day PO) on days 1 to 5. The day 1 steroid dose being part of CHOP (100 mg prednisone/prednisolone, or equivalent, PO or IV) could be used as a further component of premedication before tafasitamab infusion. L, lenalidomide; NOS, not otherwise specified; PO, orally; R, randomized; T, tafasitamab.

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