FigureĀ 6.
Strategies for stealth NK cell products. Approaches that limit T-cell responses to donor allo-antigens, specifically MHC-I, make NK cell products susceptible to recipient NK cell killing via missing-self responses. Current strategies include knocking out MHC-I and overexpressing nonclassical MHC-I molecules to protect donor NK cells from recipient lymphocyte-mediated rejection.

Strategies for stealth NK cell products. Approaches that limit T-cell responses to donor allo-antigens, specifically MHC-I, make NK cell products susceptible to recipient NK cell killing via missing-self responses. Current strategies include knocking out MHC-I and overexpressing nonclassical MHC-I molecules to protect donor NK cells from recipient lymphocyte-mediated rejection.

Close Modal

or Create an Account

Close Modal
Close Modal