Rapid availability and cost-effectiveness of B-VSTs vs recipient-specific VSTs. B-VSTs from a small number of donors are expanded in vitro and cryopreserved as a bank. They can be thawed and used immediately for multiple recipients. By contrast, recipient-specific VSTs that are manufactured from the HSCT donor, require up to 4 weeks or longer to complete manufacture and quality assurance/quality control (QA/QC) testing and are used only for a single recipient.