Figure 4.
Responses to axi-cel shown in relation with time. The response of the 57 patients is shown in relation with time. Responses evolved initially with most becoming final by 3 months. The patients with positive ctDNA at 1 month are marked with a dash by the colored boxes and their outcome tracked. At 1 month, 3 patients in CR who remained in durable remission had detectable ctDNA, whereas 5 of 6 patients who progressed by month 6 had undetectable ctDNA. Six of 7 patients initially in PR who achieved CR by 6 months had ctDNA 0 Lg/mL at 1 month. One of 2 patients initially in SD had 0 Lg/mL ctDNA at all available time points before and after axi-cel. Fourteen of 17 PR/ SD who had partial disease had detectable ctDNA at 1 month (1 was unavailable).

Responses to axi-cel shown in relation with time. The response of the 57 patients is shown in relation with time. Responses evolved initially with most becoming final by 3 months. The patients with positive ctDNA at 1 month are marked with a dash by the colored boxes and their outcome tracked. At 1 month, 3 patients in CR who remained in durable remission had detectable ctDNA, whereas 5 of 6 patients who progressed by month 6 had undetectable ctDNA. Six of 7 patients initially in PR who achieved CR by 6 months had ctDNA 0 Lg/mL at 1 month. One of 2 patients initially in SD had 0 Lg/mL ctDNA at all available time points before and after axi-cel. Fourteen of 17 PR/ SD who had partial disease had detectable ctDNA at 1 month (1 was unavailable).

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