Host responses to infection with P falciparum in early erythroblasts involve genes implicated in cell cycle regulation and dyserythropoiesis. (A) Enrichment analysis results using MSigDB Hallmark gene sets with DEGs (infected vs uninfected) detected in ProE and BasoE populations. Analysis of DEGs with log fold change > 0 (UP), and analysis of DEGs with log fold change < 0 (DOWN) are shown. Size indicates significance. Color indicates the odds ratio based on a Fisher exact test. (B) Expression of GDF15 and (C) NUF2 in ProE and BasoE populations. (D) Expression of cell cycle–related genes in ProEs and (E) BasoEs. (F-G) Expression of genes encoding ribosomal proteins in ProEs and BasoEs. Data are shown as median with 95% confidence intervals. cpm, counts per minute; TNF, tumor necrosis factor.