Figure 6.
Tumor interferon and PAX5 transcriptional network validation. (A) Cytokines IFNα2, IFNβ1, IL-6 (IFNβ2), and IFNγ measured via the meso scale discovery assay using TMD8 tumor lysates after 5-day treatment. Error bars represent SEM, n = 4. (B-D) ABC-DLBCL cell mRNA expression after 24-hour drug treatment with or without IFNβ1 stimulation for (B) PAX5, (C) EBF1, and (D) CD79B. Error bars represent SEM, n = 5. ∗, #, and ## denote P < .05 for comparison of the control, acalabrutinib, and AZD5153, respectively.

Tumor interferon and PAX5 transcriptional network validation. (A) Cytokines IFNα2, IFNβ1, IL-6 (IFNβ2), and IFNγ measured via the meso scale discovery assay using TMD8 tumor lysates after 5-day treatment. Error bars represent SEM, n = 4. (B-D) ABC-DLBCL cell mRNA expression after 24-hour drug treatment with or without IFNβ1 stimulation for (B) PAX5, (C) EBF1, and (D) CD79B. Error bars represent SEM, n = 5. ∗, #, and ## denote P < .05 for comparison of the control, acalabrutinib, and AZD5153, respectively.

Close Modal
This Feature Is Available To Subscribers Only

or Create an Account

Close Modal
Close Modal