C3AR is not expressed on normal HSPCs. (A-B) flow cytometric analysis of C3AR expression in different fractions of NBM MNCs from 2 healthy donors. C3AR stain in red and isotype control in gray. The MNCs are shown both as a histograms and contour plots. CMP, common myeloid progenitor (Lin⁻ CD34⁺ CD38⁺ CD123⁺ CD45RA⁻); GMP, granulocyte-macrophage progenitor (Lin⁻ CD34⁺ CD38⁺ CD123⁺ CD45RA⁺); HSC, hematopoietic stem cell (Lin⁻ CD34⁺ CD38⁻ CD90⁺ CD45RA⁻); LMPP, lymphoid-primed multipotent progenitor (Lin⁻ CD34⁺ CD38⁻ CD45RA⁺); MEP, megakaryocyte-erythroid progenitor (Lin⁻ CD34⁺ CD38⁺ CD123⁻ CD45RA⁻); MPP, multipotent progenitor (Lin⁻ CD34⁺ CD38⁻ CD90⁻ CD45RA⁻).