CD11c deficiency leads to impaired neutrophil maturation. (A) Number of total neutrophils, preneutrophils, and immature and mature neutrophils in the BM of WT and CD11c KO mice. Data are mean ± SEM of 3 experiments. (B) Maturation of splenic neutrophils. Left, representative histogram overlay analysis by flow cytometry; right, data are mean ± SEM of mean fluorescence intensity (MFI) of 3 experiments. (C-D) Giemsa staining and electron microscopy images of WT and CD11c KO BM neutrophils. Representative images of 3 independent experiments with the same pattern. SEM, standard error of the mean.