Progression-free survival and overall survival. (A) PFS: 9 PFS events occurred after a median observation time of 38.4 months (range, 3.7-44.9 months). The 3-year PFS rate was 79.9%, and the median PFS was not reached. (B) PFS and del(17p): no PFS event occurred in the 15 patients with a sole TP53 mutation (blue). PFS after 36 months in patients with del(17p) and/or TP53 mutation (red) was 67.6% (P = .012). (C) PFS and IGHV: In patients with mutated IGHV (red), no disease progression occurred. In patients with unmutated IGHV (blue), the 36-month PFS was 74.0 % (P = .147). (D) OS: 3 OS events occurred, the 3-year OS rate was 92.6%, and the median OS was not reached.