Figure 1.
Flowchart. Transplanted patients were included in the study if they fulfilled the following criteria: (1) age at first alloSCT ≥15 years, (2) transplant performed between January 2008 and December 2018, and (3) underlying IEI diagnosis of CGD or CID. Matching criteria were (1) decade of birth, (2) age at last review greater than index patient age at alloSCT, and (3) one of 2 IEI categories (CGD vs CID, including profound T-cell deficiency, CVID, and IDS). Patients in the CID category were further matched by disease severity (including autoimmune/inflammatory manifestation and/or malignant lymphoproliferative disease) regardless of the date of this complication. A random draw without replacement was then performed to select ≤3 controls per index case.

Flowchart. Transplanted patients were included in the study if they fulfilled the following criteria: (1) age at first alloSCT ≥15 years, (2) transplant performed between January 2008 and December 2018, and (3) underlying IEI diagnosis of CGD or CID. Matching criteria were (1) decade of birth, (2) age at last review greater than index patient age at alloSCT, and (3) one of 2 IEI categories (CGD vs CID, including profound T-cell deficiency, CVID, and IDS). Patients in the CID category were further matched by disease severity (including autoimmune/inflammatory manifestation and/or malignant lymphoproliferative disease) regardless of the date of this complication. A random draw without replacement was then performed to select ≤3 controls per index case.

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