CN analysis of 5 tFL-PMBLsig-pos cases. (A) Heatmap showing CN changes by chromosomal location for each tFL-PMBLsig-pos case. (B-D) Graphs showing more detailed CN changes by location in chromosomes 2 (B), 12 (C), and 16 (D). Genes of note are labeled and highlighted with a dotted red line and include REL on chromosome 2 (gains in 3 of 5 cases; case 5/FL1122T2 illustrated), STAT6 on chromosome 12 (gains/amplification in 3 of 5 cases; case 4/FL1179T2 illustrated), and IL4R on chromosome 16 (gains in 2 of 5 cases; case 1/EX00406 illustrated).