Morphology and immunophenotype of tFL-PMBLsig-pos cases. (A) The tFL-PMBLsig-pos (case 2) is composed of sheets of large B cells with predominantly centroblastic cytology that coexpress CD20 and CD10 (not shown). (B) CD23 is diffusely positive. (C) CD30 shows prominent background nonspecific staining with only rare strongly positive cells. (D) A large subset of the neoplastic B cells expresses MAL and (E) CD200 but is negative for (F) CD273/PDL2. Original magnifications ×500 (A) and ×200 (B-F); A, hematoxylin and eosin stain and B-F, immunohistochemical stain with hematoxylin counterstain.