Figure 2.
Virus-specific T cells with TCR nucleotide sequences found in the T-cell products could be identified in patients with and without detectable viral loads. The total numbers (Σ) of different virus-specific TCR nucleotide sequences are shown for each product (above each bar). Patients are grouped according to detectable viral loads after infusion of the T-cell product. Shown are the percentages of different CMV- (A), EBV- (B), and AdV- (C) specific TCR nucleotide sequences that could be detected only after infusion of the products (color scale), before and after infusion (light color scale), or that could not be detected (white). The numbers of different TCR nucleotide sequences that were found only after infusion, shown as percentages in bar plots with the median and iIQR, were compared between patients with and without CMV viral load (D) and with and without EBV viral load (E). Statistical differences were assessed with the Mann-Whitney t test (D-E). ∗P < .05; ∗∗P < .01.

Virus-specific T cells with TCR nucleotide sequences found in the T-cell products could be identified in patients with and without detectable viral loads. The total numbers (Σ) of different virus-specific TCR nucleotide sequences are shown for each product (above each bar). Patients are grouped according to detectable viral loads after infusion of the T-cell product. Shown are the percentages of different CMV- (A), EBV- (B), and AdV- (C) specific TCR nucleotide sequences that could be detected only after infusion of the products (color scale), before and after infusion (light color scale), or that could not be detected (white). The numbers of different TCR nucleotide sequences that were found only after infusion, shown as percentages in bar plots with the median and iIQR, were compared between patients with and without CMV viral load (D) and with and without EBV viral load (E). Statistical differences were assessed with the Mann-Whitney t test (D-E). ∗P < .05; ∗∗P < .01.

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