Figure 3.
PheWAS analysis of patients with primary myelofibrosis. Our primary myelofibrosis cohort was analyzed for all grouped diagnostic codes (phecodes) within 360 days of diagnosis. Based on this phecode list, we conducted a phenome-wide associated (PheWAS) study to test the association of each phecode with survival. We used the Cox proportional hazards model adjusted for the DIPSS predictors with Bonferroni correction to account for multiple comparisons. Diagnoses above P < .00013 on the volcano plot represent significance after Bonferroni correction.

PheWAS analysis of patients with primary myelofibrosis. Our primary myelofibrosis cohort was analyzed for all grouped diagnostic codes (phecodes) within 360 days of diagnosis. Based on this phecode list, we conducted a phenome-wide associated (PheWAS) study to test the association of each phecode with survival. We used the Cox proportional hazards model adjusted for the DIPSS predictors with Bonferroni correction to account for multiple comparisons. Diagnoses above P < .00013 on the volcano plot represent significance after Bonferroni correction.

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