FigureĀ 2.
Selection of TCR/CD3-CAR NK-92 cell line with the highest purification efficacy. (A) Experimental setup for nonviral TCR-to-CAR replacement (in T cells) and subsequent NK-92 cell-mediated depletion of residual TCR-unedited cells. (B) Flow cytometric detection of residual TCR-wild-type T cells after coculture with TCR/CD3-CAR NK-92 cells (left) or under control conditions (upper right) and summary of data (bottom right).

Selection of TCR/CD3-CAR NK-92 cell line with the highest purification efficacy. (A) Experimental setup for nonviral TCR-to-CAR replacement (in T cells) and subsequent NK-92 cell-mediated depletion of residual TCR-unedited cells. (B) Flow cytometric detection of residual TCR-wild-type T cells after coculture with TCR/CD3-CAR NK-92 cells (left) or under control conditions (upper right) and summary of data (bottom right).

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