CN landscape of pediatric mPTLD and comparisons with previously published cohorts. (A) Global CN profile of 23 B-cell post-SOT mPTLD. x-axis represents chromosomes from 1 to Y and p to q. The y-axis indicates the frequency of each genomic alteration among the analyzed cases; CN gains are represented in blue, and CN losses are depicted in red. Chromosomal bands of regions altered in more than 10% of cases are indicated in the plot. (B-C) CN profile comparison with previously published data on BL³³ (B) and DLBCL⁹ (C) in IMC patients. Asterisks indicate significant differences between both groups according to Fisher exact test raw P < .1, considering a minimum number of altered cases n = 3.