Progression-free survival and OS according to CKT status. In the CIT arm (A) and the pooled venetoclax arms (B), PFS is significantly shorter in patients with CKT (red curve) than in those with nCKT (blue curve). Patients with CKT also show significantly shorter OS than patients with nCKT in the CIT arm (C), whereas there is no OS difference in the pooled venetoclax arms (D).