Clinical and MRD responses according to CKT status. Response to treatment (A) and MRD status in peripheral blood at month 15 (B) based on the CKT status and treatment group. There are no significant differences in the ORR or CRR between patients with CKT and nCKT in neither the CIT nor the ven group (A). In the CIT arm, patients with CKT have a significantly lower uMRD rate at MO15 (B), whereas there is no difference between CKT and nCKT with regard to uMRD in the pooled venetoclax arms. CR, complete response; CRR, CR rate; ORR, overall response rate; PR, partial response; ven, pooled venetoclax arms.