Molecular regulatory network in leukemia. (A-B) The number of TF-target pairs with high correlation (R > 0.05; P value < .01) in (A) leukemia subtypes and (B) cell lines. (C-D) The number of mRNA-circRNA pairs with high correlation (R > 0.05; P value < .01) in (C) patients with leukemia and (D) leukemia cell lines. (E) TF-target regulatory modules of HOXA9 in AML from LeukemiaDB data. (F) mRNA-lncRNA regulatory modules of NOTCH1 in T-ALL from LeukemiaDB data.