FigureĀ 4.
DLI-derived memory T cells are engrafted and recruited in the immune response. (A) Venn diagram shows the clonal overlap in number of unique clonotypes of patient #1. The bar graph shows the clonal overlap at T7 with the DLI separately for patients who received DLI as frequency of the total number of unique clonotypes at T7, whereas their average is shown in the pie chart. (B) Left graph shows the relative abundance of clonotypes overlapping between the DLI and T7 of patient #1. Roman numerals indicate the clonotype fractions shown in (A). The top 10 most abundant clones of fraction III are highlighted in color. The bar graph shows the abundance of overlapping clonotypes at T7 separately for patients who received DLI, whereas their average is shown in the pie chart. (C) DLI-derived engrafted clonotypes (fraction III) of each patient were analyzed for the presence of public TCR sequences known to harbor specificity for CMV-, Epstein-Barr virus- or influenza-derived epitopes.

DLI-derived memory T cells are engrafted and recruited in the immune response. (A) Venn diagram shows the clonal overlap in number of unique clonotypes of patient #1. The bar graph shows the clonal overlap at T7 with the DLI separately for patients who received DLI as frequency of the total number of unique clonotypes at T7, whereas their average is shown in the pie chart. (B) Left graph shows the relative abundance of clonotypes overlapping between the DLI and T7 of patient #1. Roman numerals indicate the clonotype fractions shown in (A). The top 10 most abundant clones of fraction III are highlighted in color. The bar graph shows the abundance of overlapping clonotypes at T7 separately for patients who received DLI, whereas their average is shown in the pie chart. (C) DLI-derived engrafted clonotypes (fraction III) of each patient were analyzed for the presence of public TCR sequences known to harbor specificity for CMV-, Epstein-Barr virus- or influenza-derived epitopes.

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