CRP, SAP, and PTX3 concentrations in ITP sera and their relationship with macrophage phagocytosis and the platelet count. The concentrations of CRP, SAP, and PTX3 were determined for each ITP sera and explored for a potential correlation with the magnitude of phagocytosis and the platelet count. The concentrations of (A-C) CRP, (D-F) SAP, and (G-I) PTX3 were correlated with the phagocytic index among indirect MAIPA-positive ITP sera in panels A, D, and G the platelet count across all patients in panels B, E, and H, or the platelet count among indirect MAIPA-positive patients in panels C, F, and I. Data was assessed for a normal (Gaussian) distribution by the Shapiro-Wilk test; Pearson correlation coefficients were computed for panels with Gaussian distribution in panels D-G; Spearman correlation coefficients were computed for data with non-Gaussian distribution in panels A-C, E, F, H, and I. A simple linear regression line for visualization is depicted.