Summary of HRQoL overall scores by IPSS-R score in MDS or MDS/MPN overlap. Number of participants (N) with MDS or MDS/MPN overlap in each IPSS-R strata: very low/low (N = 149), intermediate (N=54), high/very high (N = 58). Estimates based on ANCOVA model adjusted for age. Estimates and P value based on linear regression of QOL score and IPSS-R score adjusted for age.