TP53 mutations and del(17p) based on CLL and HCMBL. Note that only TP53 mutations with VAF >10% were considered. Rate of mutations and del(17p) in CLL (A) and HCMBL (B) cases. Gold indicates single-hit (∗ denotes multihit based on cnLOH), and blue indicates multihit TP53. (C) VAF of TP53 mutations. Box plot (quartiles and median shown) and violin plots show distribution. (D) Percent of cells with del(17p) by FISH. (E) Location, type, and counts of TP53 mutations. Num, number.