Native post-alloSCT CD146⁺MSC show similar differential expression for proliferation regulating genes as CFU-F-derived MSC. RNAseq analysis was performed in native CD146⁺MNC derived before and after alloSCT from 4 patients. (A) Heatmaps of total differentially expressed genes (rows) in CD146⁺/CD45^–/HLA-DR^– MNC pre- and post-alloSCT (columns). (B) Authentication of DGE in post- vs pre-alloSCT MSC according to the MSC phenotype, ie, post-alloSCT CFU-F–derived MSC from patients 1 to 5 and post-alloSCT CD146⁺MNC from patients 8 to 10 and 14. (C) Enriched gene sets of 67 common downregulated genes from (B) in CD146⁺MSC post-alloSCT vs CD146⁺MSC pre-alloSCT. (D) Selected significantly downregulated genes in the native CD146⁺MNC (complete list of 67 downregulated genes in supplemental Table 2).