OS and RFS of HLH-LT and non–HLH-LT groups. (A) OS and RFS of patients with CRS (any grade) and HLH-LTs (CRS + HLH-LT), those with ASTCT grade 3 to 5 CRS (HG-CRS) without HLH-LTs (HG-CRS, no HLH-LT), and those with no CRS or ASTCT grade 1 to 2 CRS without HLH-LTs (NLG-CRS, no HLH-LT). (B) OS and RFS of patients with ASTCT grade 1 to 2 CRS (LG-CRS) and grade 3 to 5 CRS (HG-CRS), with and without HLH-LT. (C) OS and RFS of group without HLH-LT (no HLH-LT), those with HLH-LT and peak ferritin ≥10 000 and < 100 000 ng/mL (HLH-LT, 10 to <100 000), and those with HLH-LT with peak ferritin ≥100 000 ng/mL (HLH-LT, ≥100 000). Survival curves were generated with Kaplan-Meier method and compared using log-rank tests with significance level of P < .05.