Path analysis diagram showing direct and indirect relationships between blood oxygenation measures (red boxes, left) and cognition (orange boxes, right) in patients. Mediation pathways via unweighted (blue), streamline-weighted (green), and fractional anisotropy-weighted (lavender) network measures appear toward the center of the diagram. Standardized coefficients are shown on solid lines for relationships with P < .05. The double-headed arrow between processing speed index and working memory index reflects a residual covariance term. FA, fractional anisotropy; fED, full-network edge density; fGE, full-network global efficiency; FSIQ, full-scale intelligence quotient; PSI, processing speed index; sGE, subnetwork global efficiency; SpO2, peripheral oxygen saturation; WMI, working memory index.
